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Systematic review of 6 phase II and III trials of teriflunomide in relapsing multiple sclerosis reports ALT elevations above 3 times ULN in 12-14% of teriflunomide vs 7% of control subjects; no mention of clinically apparent liver injury).
improvements seen with methotrexate were significantly greater than those with leflunomide
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We do not evaluate the conventional DMARDs or other rheumatoid arthritis treatments, or compare them with biologics.
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Encourage patients 50 years and older to get the Shingrix vaccine.
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Quality assessment was undertaken using GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria.
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Since most people (more than 95 percent of individuals) with lupus will test positive, a negative ANA test can be helpful in excluding that diagnosis.
Central venous catheters may be used to take multiple blood samples without the necessity of repeatedly sticking the patient with a needle.
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