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The early recognition and appropriate management of neuropathy in the patient with diabetes is important for a number of reasons: 1) nondiabetic neuropathies may be present in patients with diabetes and may be treatable; 2) a number of treatment options exist for symptomatic diabetic neuropathy; 3) up to 50% of DPN may be asymptomatic and patients are at risk of insensate injury to their feet; 4) autonomic neuropathy may involve every system in the body; and 5) cardiovascular autonomic neuropathy causes substantial morbidity and mortality.
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The panel was in broad agreement that the treatment benefit in the trial, though it achieved statistical significance, was too small to support the label upgrade.
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In addition, no evidence of damage to genetic material was noted in an in vitro alkaline elution assay using rat hepatocytes, a V-79 mammalian cell forward mutation study, an in vitro chromosome aberration study in CHO cells, or an in vivo chromosomal aberration assay in mouse bone marrow.
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Resins can interfere with the absorption of other medications, including digoxin, thyroid hormones, and some beta blockers, calcium-channel blockers, and diuretics.
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The project team including the chair of the Expert Working Group (EWG), along with input of individual members of the EWG or corresponding group, used these statements and the underlying evidence to draft recommendations.
The use of intravenous (IV) iron has been growing over the last decade, and recent reports have indicated that, of the IV iron products, the highest risk for anaphylaxis and other serious allergic reactions occurs with iron dextran products.
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Patient should consult prescriber for additional questions.
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In 2012, a called the Post-Finasteride Syndrome Foundation was formed with the primary goal of finding a cure for the reported syndrome and a secondary goal of raising awareness.
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If you have any of these conditions, you may need a dose adjustment or special tests to safely take ezetimibe.
When muscle symptoms subside, a lower dose or a different statin can be tried.
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